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Experiment 1: Following Chromosomal DNA Movement through Meiosis
Part 1 – Meiotic Division Bead Pictures without Crossing Over – You must provide pictures of your bead manipulations at each stage.
Part 2: Meiotic Division Beads Diagram with Crossing Over – You must provide pictures of your bead manipulations at each stage.
1. Were any of your daughter cells genetically identical at the end of Part I above? What about Part II? What does this tell you about the importance of crossing over?
2. What must occur during interphase for meiosis to be successful?
3. When does the diploid number become haploid during meiosis?
4. Why did you use non-sister chromatids to demonstrate crossing over?
5. What combinations of alleles could result from a crossover between a chromosome having genes BD and a chromosome having genes bd?
6. Blue whales have 44 chromosomes in every cell. Determine how many chromosomes you would expect to find in the following:
Daughter Cell from Meiosis I:
Daughter Cell from Meiosis II:
7. What is the difference between a chromosomal mutation and a gene mutation?
Experiment 2: The Importance of Cell Cycle Control
Data – Enter your karyotype abnormalities below. Explain the abnormality in terms of chromosome number and structure. Do not post pictures of the karyotypes themselves.
1. What is your hypothesis as to what differences you might observe when comparing the karyotypes of human cells which experience normal cell cycle control versus cancerous cells (which experience abnormal, or a lack of, cell cycle control)?
2. Did your results confirm or disprove your hypothesis? Why or why not? Be specific!
3. Suppose a person developed a mutation in a skin cell which results in cancer, but the cancer was effectively treated with a cocktail of cancer-fighting techniques. Is it possible for this person’s offspring to inherit this cancer-causing mutation? Why or why not? Be specific!
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